COLTENE Holding AG develops, manufactures, and sells disposables, tools, and equipment for dentists and dental laboratories across Europe, the Middle East, Africa, North America, Latin America, and Asia/Oceania. Its product range includes restoration and endodontics products, prosthetics, treatment auxiliaries, infection control products, rotary instruments, and laboratory products. The company was formerly known as Medisize Holding AG and changed its name to COLTENE Holding AG in April 2008. It was incorporated in 2005 and is headquartered in Altstätten, Switzerland.