ACADIA Pharmaceuticals IncRaises 2026 DAYBUE sales guidance on strong Q2 performance and rapid uptake of new STIX formulation.

Acadia Pharmaceuticals raised its full-year 2026 net sales guidance for DAYBUE to $480 million to $510 million, up from the prior range of $460 million to $490 million, driven by strong second-quarter performance and rapid uptake of the new DAYBUE STIX powder formulation. Total second-quarter revenues reached $308 million, a 17% adjusted year-over-year increase, with DAYBUE net sales of $125 million growing 30% and NUPLAZID net sales of $183 million up 10% on an adjusted basis. The company reaffirmed its 2026 NUPLAZID sales guidance of $760 million to $790 million and updated its total revenue outlook to $1.24 billion to $1.30 billion, while lowering R&D expense guidance to $355 million to $380 million due to a business development milestone shifting to 2027. Management also highlighted the upcoming Phase II readout for remlifanserin in Alzheimer's disease psychosis, expected in September to October 2026, with peak sales potential estimated at $4 billion across Alzheimer's disease psychosis and Lewy body dementia psychosis.
ACADIA Pharmaceuticals IncRaises 2026 DAYBUE sales guidance on strong Q2 performance and rapid uptake of new STIX formulation.