BioCryst raises 2026 total revenue guidance to $690 million to $715 million

Earnings
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BioCryst Pharmaceuticals raised its full-year 2026 total revenue guidance to a range of $690 million to $715 million, driven by the closing of a navenibart European license agreement. The company maintained its ORLADEYO revenue guidance of $625 million to $645 million and reduced its non-GAAP operating cost guidance to $420 million to $440 million from a prior range of $450 million to $470 million. Second-quarter ORLADEYO revenue reached $158.2 million, contributing to a non-GAAP operating profit of $113.2 million. The company also began shipping ORLADEYO oral pellets for pediatric patients and reported 47 prescriptions through July 31, ahead of full-year expectations. BioCryst ended the quarter with over $350 million in cash, cash equivalents, and investments, and generated positive cash flow even excluding upfront proceeds from the license agreement.

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