Apellis Pharmaceuticals IncBiogen is suspending several Apellis pipeline programs, including Phase II studies for Empaveli in new indications, and reducing R&D staff.
Biogen is scaling back Apellis Pharmaceuticals' research pipeline and reducing R&D staff weeks after completing its $5.6 billion acquisition. The company has suspended several legacy programs, including Phase II studies for Empaveli in delayed graft function and focal segmental glomerulosclerosis, citing strategic evaluations and recruitment challenges. Biogen is maintaining focus on a key Phase II trial for the eye disease therapy Syfovre in combination with an RNA interference inhibitor, signaling its primary interest in the pegcetacoplan franchise marketed as Empaveli and Syfovre. Forecasts suggest the franchise could generate $785 million by 2032. The future of Apellis' preclinical assets, such as RNA-based therapies and a gene-editing project, remains unclear.
Apellis Pharmaceuticals IncBiogen is suspending several Apellis pipeline programs, including Phase II studies for Empaveli in new indications, and reducing R&D staff.
Biogen IncBiogen is scaling back the acquired pipeline to focus on Syfovre combination trial, but the net impact on Biogen is mixed: cost savings vs. lost pipeline value.