CervoMed to Present Five Studies on Neflamapimod for Dementia with Lewy Bodies at AAIC 2026

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CervoMed announced it will feature five presentations at the Alzheimer's Association International Conference 2026 in London from July 12 to 15, including four on its oral drug candidate neflamapimod for dementia with Lewy bodies. The presentations will cover exploratory Phase 2 analyses showing neflamapimod slowed clinical worsening in patients with low plasma p-tau181 and higher drug concentrations, its impact on basal forebrain atrophy as measured by MRI from the RewinD-LB trial, the plasma drug exposure-response relationship focusing on pharmacokinetic-pharmacodynamic relationships, and the first clinical data for an 80 mg twice-daily dose from a 24-week open-label study assessing safety, tolerability, and pharmacokinetics. A fifth presentation will address the development of a Goal Area Inventory for dementia with Lewy bodies using Goal Attainment Scaling to assess treatment response. Neflamapimod is an investigational oral small molecule that inhibits p38 MAP kinase, and the company is seeking a strategic partner to advance it into a Phase 3 trial for dementia with Lewy bodies.

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Five presentations at AAIC 2026 on neflamapimod, including positive Phase 2 analyses and first clinical data for a new dose, advancing the drug candidate.

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