Changchun High & New Technology Industries Group IncClinical trial application for GenSci148 injection accepted, a novel VEGF multi-blocker with potential for extended dosing intervals.

The clinical trial application for the domestically produced drug registration of GenSci148 injection, developed by Changchun High-Tech subsidiary GeneScience Pharmaceuticals, has been accepted by the National Medical Products Administration. The indications are neovascular age-related macular degeneration, diabetic macular edema, and retinal vein occlusion. GenSci148 is a VEGF multi-blocker independently developed by GeneScience Pharmaceuticals, classified as a Class 1 therapeutic biological product. Based on the proprietary ProlonXTM long-acting platform, it can simultaneously bind VEGF-A, VEGF-C, VEGF-D, and Ang-2, potentially extending dosing intervals and reducing treatment burden. The company stated that this acceptance aligns with its strategic plan in the ophthalmology field, but the subsequent progress and results of the clinical trial remain uncertain.
Changchun High & New Technology Industries Group IncClinical trial application for GenSci148 injection accepted, a novel VEGF multi-blocker with potential for extended dosing intervals.