Fulcrum Therapeutics Fair Value Slashed 71% to $5.43 After Pociredir Exit

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Fulcrum Therapeutics' modeled fair value has been cut by roughly 71%, from about US$19.00 to approximately US$5.43, following the discontinuation of pociredir and a shift in analyst focus to the company's cash position and strategic alternatives. Several firms, including JPMorgan, Piper Sandler, Stifel, Truist, Leerink, and H.C. Wainwright, moved to more cautious ratings, with price targets reset to a range of about US$3 to US$4, down from prior targets that were several times higher. Truist estimates cash value at about US$4 per share, which some investors may view as a backstop while the company reviews options. Goldman Sachs suspended its rating entirely after removing pociredir from pipeline models, indicating insufficient basis to frame upside or downside scenarios. The fair value revision also reflects adjustments to modeled revenue growth, net profit margin, future P/E, and discount rate.

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Fulcrum Therapeutics Inc
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Fair value slashed 71% after pociredir discontinuation; analysts cut price targets to $3-$4, reflecting loss of pipeline value and focus on cash.

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H.C. Wainwright & Co.Private± Mixed
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