GSK Specialty Medicines Sales Rise 14% as HIV Patent Cliff Looms

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GSK's Specialty Medicines unit, which now accounts for more than 40% of the company's sales and is expected to exceed 50% of total revenues by 2031, posted 14% sales growth at CER in the first half of 2026 on double-digit gains across HIV, Respiratory, Immunology & Inflammation and Oncology. New long-acting HIV injectables Cabenuva and Apretude account for around 25-30% of total HIV sales, while newer oncology drugs Jemperli and Ojjaara and recent launches including Blenrep, Exdensur and Penmenvy broaden the growth base, and GSK expects low double-digit percentage sales growth in the segment for 2026 at CER. The company now expects more than 20 phase III starts in 2026, more than twice the 10 originally contemplated, and has 19 assets in late-stage development or under regulatory review, with FDA decisions on bepirovirsen for chronic hepatitis B and neladalkib for non-small cell lung cancer expected later this year. GSK faces the loss of exclusivity for dolutegravir, the backbone of HIV medicines including Tivicay, Triumeq and Dovato, with patents expected to begin expiring in major markets around 2028-2029; dolutegravir-based products generated £2.74 billion in sales in the first half of 2026. GSK expects to launch twice-yearly long-acting injectables for treatment and PrEP between 2028 and 2030, and competes in Specialty Medicines with AstraZeneca, Merck, Sanofi, Gilead, Pfizer, J&J and Novartis, among others.

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Specialty Medicines sales rose 14% at CER in H1 2026 on double-digit gains across HIV, Respiratory, Immunology & Inflammation and Oncology, with GSK guiding to low double-digit growth for 2026.

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