Halozyme Therapeutics IncHalozyme's ENHANZE technology is licensed to Incyte for subcutaneous cancer therapy, with upfront and milestone payments.
Halozyme Therapeutics has entered a global collaboration and license agreement with Incyte to develop additional subcutaneous formulations of Incyte's INCA033989, a first-in-class mutant calreticulin-targeted monoclonal antibody for a cancer indication. The partnership will evaluate subcutaneous dosing using Halozyme's proprietary ENHANZE drug delivery technology in patients with mutCALR-expressing myeloproliferative neoplasms. Incyte gains rights to develop and commercialize the ENHANZE technology with its mutCALR program and holds an option to nominate up to two additional targets. Halozyme will receive an undisclosed upfront payment, milestone payments, and royalties on future net sales. Halozyme's royalty revenues reached $240.7 million in the first quarter of 2026, up 43% year over year, driven by demand for partnered products including subcutaneous Darzalex and Phesgo.
Halozyme Therapeutics IncHalozyme's ENHANZE technology is licensed to Incyte for subcutaneous cancer therapy, with upfront and milestone payments.
Incyte CorporationIncyte gains rights to develop subcutaneous formulation of its cancer drug using Halozyme's technology, potentially improving its product.
Johnson & Johnson