Myriad Genetics IncExpanded availability of Precise MRD test to three new cancer types and positive study results demonstrating superior detection.

Myriad Genetics announced expanded availability of its Precise MRD test to patients with breast, colorectal and renal cancers, a move that broadens access to the ultrasensitive circulating tumor DNA assay for more than 6 million individuals living with these cancers in the U.S. The whole-genome sequencing-based test tracks up to 1,000 patient-specific variants and is designed for use across the cancer care continuum, from neoadjuvant therapy through post-surgical assessment and long-term surveillance. The company also published results from the prospective MONITOR-Breast study in Future Oncology, which showed that serial ctDNA monitoring during neoadjuvant therapy identified 44% more patients at risk for residual disease than testing at a single post-treatment timepoint alone. In the study of 154 patients with Stage I–III breast cancer, Precise MRD detected ctDNA in 93% of patients at baseline and predicted pathological complete response with 100% specificity, while patients who remained ctDNA positive at the end of neoadjuvant therapy were 47 times more likely to stay ctDNA positive after surgery.
Myriad Genetics IncExpanded availability of Precise MRD test to three new cancer types and positive study results demonstrating superior detection.