Pacific Biosciences of CaliforniaPacBio announces SPRQ-Nx chemistry and software update for Vega, boosting output and cutting cost per gigabase.

PacBio announced the upcoming release of SPRQ-Nx chemistry and a software update for its Vega benchtop sequencing system, increasing HiFi data output from 60 Gb to 90 Gb per run while lowering the U.S. list price from $1,100 to $995. The higher output and lower price reduce cost per gigabase by approximately 40%, and the update introduces two-hour and four-hour run options alongside new 5hmC, 5mC, and 6mA methylation callers that bring Vega’s multiomic capabilities in line with the high-throughput Revio system. The software also adds user login and audit-tracking features to support 21 CFR Part 11 compliance, and DNA input requirements drop from 2 µg to as low as 500 ng, enabling up to 96-sample multiplexing with PureTarget panels. PacBio plans to ship the new chemistry and make the software available for download by the end of the month.
Pacific Biosciences of CaliforniaPacBio announces SPRQ-Nx chemistry and software update for Vega, boosting output and cutting cost per gigabase.