Review of Over 50 Studies Finds Non-Prescription CBD Products Lack Therapeutic Efficacy, Supporting Artelo's Optimized ART12.11

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โดย GlobeNewswire·Read original
Summary · why it matters

A new review published in the British Journal of Clinical Pharmacology finds that widely sold non-prescription CBD products at typical doses fail to provide adequate exposure for a positive biological effect. The analysis of over 50 studies showed that low-dose CBD, defined as 2.5 milligrams per kilogram or less or 175 milligrams per day or less, had little to no evidence of therapeutic value, with peak plasma exposure and total drug exposure 5 to 100 times lower than approved therapeutic doses for epilepsy. The review also identified significant drug-drug interactions with medications including amitriptyline and hydromorphone, raising safety concerns. Artelo Biosciences says its proprietary CBD cocrystal composition ART12.11 aims to address this challenge by increasing bioavailability compared with CBD alone, and the company plans to advance it into clinical development.

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Biotech & Genomic Medicine▲ · 1 stocks
Artelo Biosciences Inc
ARTL
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The article highlights that non-prescription CBD products lack efficacy due to low bioavailability, while Artelo's proprietary ART12.11 aims to address this with optimized formulation, supporting its clinical advancement.

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