Royalty Pharma PlcRoyalty Pharma acquires royalty interest in cliramitug for up to $425 million, providing a new revenue stream.
Royalty Pharma has acquired a portion of Neurimmune's royalty interest in AstraZeneca's cliramitug for up to $425 million, including $125 million upfront. The deal gives Royalty Pharma a 3% to 4% royalty on worldwide net sales of the Phase 3 TTR-fibril-depleting antibody, which targets ATTR amyloidosis with cardiomyopathy. An additional $125 million is payable in the first quarter of 2027, with the remaining $175 million tied to clinical and regulatory milestones. Cliramitug is currently in the Phase 3 DepleTTR-CM trial, with results expected in 2028, and AstraZeneca has set a peak sales target of $3 billion to $5 billion. The ATTR-CM market surpassed $7 billion in 2025, growing over 40% year-over-year.
Royalty Pharma PlcRoyalty Pharma acquires royalty interest in cliramitug for up to $425 million, providing a new revenue stream.
AstraZeneca PLCAstraZeneca's cliramitug is in Phase 3 with peak sales target of $3-5 billion; royalty deal validates its potential.
Neurimmune receives up to $425 million for its royalty interest in cliramitug, providing significant cash inflow.