State Street's Health Care Select Sector SPDR ETF offers a significantly lower expense ratio and far greater assets under management than the Invesco Pharmaceuticals ETF. The SPDR fund charges just 0.08% compared with 0.57% for the Invesco fund, and holds $40.9 billion in assets versus $353.9 million. While the Invesco ETF focuses exclusively on 29 pharmaceutical companies, the SPDR fund provides broader exposure across the healthcare sector with 59 holdings. The SPDR ETF also delivers a higher trailing dividend yield of 1.6%, though the Invesco fund has posted stronger total returns over the past year at 49.9% against 19.8%.
AbbVie Inc
Abbott Laboratories
Johnson & Johnson
Eli Lilly and Company
Invesco Plc
State Street Corp