Gilead Sciences IncGilead's remdesivir is being evaluated in an experimental Ebola trial, potentially expanding its use and demand.

The World Health Organization has launched an experimental Ebola trial in the Democratic Republic of Congo, where the Bundibugyo strain has killed more than 500 people. The study is evaluating Mapp Biopharmaceutical's monoclonal antibody cocktail MBP134 and Gilead Sciences' antiviral remdesivir alongside optimized supportive care in Ituri province. It is structured as an adaptive platform trial that can continue through future outbreaks if the current epidemic ends before enough patients are enrolled. The primary endpoint is all-cause mortality 28 days after enrollment, with secondary endpoints including viral clearance and pregnancy outcomes. Researchers plan to enroll several hundred patients, who may receive MBP134, remdesivir, a combination, or supportive care alone.
Gilead Sciences IncGilead's remdesivir is being evaluated in an experimental Ebola trial, potentially expanding its use and demand.
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Union Pacific CorporationMapp Biopharmaceutical's monoclonal antibody MBP134 is being tested in the WHO-led Ebola trial, potentially leading to future demand.