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CARsgen Therapeutics Holdings Ltd

CARsgen Therapeutics Holdings Limited is an investment holding company that discovers, develops, and commercializes chimeric antigen receptor T (CAR-T) cell therapies for hematological malignancies, solid tumors, and autoimmune diseases in China. Its products include Zevor-cel (CT053) for relapsed/refractory multiple myeloma. The company is also developing autologous CAR-T candidates such as CT041, which targets Claudin 18.2 and is in phase II/III trials for gastric/gastroesophageal junction cancer and pancreatic cancer, and in phase I trials for gastric or pancreatic cancer; CT011 in phase I for hepatocellular carcinoma (HCC); and CT071 in phase I for relapsed/refractory multiple myeloma, relapsed/refractory primary plasma cell leukemia, relapsed/refractory plasma cell leukemia, and newly diagnosed multiple myeloma. In addition, it is developing CT0590 and CT0596, which target B-cell maturation antigen and are in phase I for R/R MM and PCL; KJ-C2219 in phase I for B-cell malignancies, systemic lupus erythematosus, and systemic sclerosis; and KJ-C2320 for acute myeloid leukemia (AML) in phase I. The company also develops KJ-C2526 in pre-clinical stage for AML, other malignancies, and senescence; KJ-C2527 in pre-clinical stage for gastric cancer; CT1390B in pre-clinical stage for AML; and KJ-C2529 in pre-clinical stage for B-cell malignancies. Additionally, it engages in drug research and development, manufacture, and import and export handling. The company was founded in 2014 and is headquartered in Shanghai, China.

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Biotech & Genomic Medicine

CARsgen Therapeutics posts 62 million yuan half-year revenue as solid tumor CAR-T awaits market test

CARsgen Therapeutics disclosed its first-half 2026 results, reporting revenue of 62 million yuan, mainly from its autologous BCMA CAR-T product Zevorcabtagene Autoleucel. Thanks to higher sales of Zevorcabtagene Autoleucel, gross profit reached 42 million yuan, up 13 million yuan from 29 million yuan in the same period of 2025. Net loss for the period was 70.84 million yuan, compared with annual net losses of 748 million yuan, 798 million yuan and 98 million yuan from 2023 to 2025. With the approval in June 2026 of the world's first solid tumor CAR-T product, Satricabtagene Autoleucel, the market expects it to add new volume in the second half. Satricabtagene Autoleucel is listed at 990,000 yuan per dose. The company expects 200 orders in 2026 and forecasts peak sales of 2 billion yuan in the mainland China market, reaching that peak in about four to five years. As of the end of June 2026, the company had cash and cash equivalents of about 1.4 billion yuan, up 277 million yuan from 1.123 billion yuan at the end of 2025. The company judges that its existing capital reserves can support operations until 2030.
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