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Zhaoke Ophthalmology Limited

Zhaoke Ophthalmology Limited operates as an ophthalmic pharmaceutical company in Hong Kong, Mainland China, South Korea, and internationally. The company develops Cyclosporine A ophthalmic gel for the treatment of dry eye disease (DED); RGN-259, an eye drop indicated for moderate-to-severe DED; CsA/rebamipide ophthalmic gel for anti-inflammation and tear film stabilization; and IC-265 in Phase II clinical trial for the treatment of allergic conjunctivitis. It also engages in the development of NVK-002, an ophthalmic solution to control or slow myopia progression in children and adolescents; BRIMOCHOL PF and Carbachol PF pupil-modulating eye drops to correct for the loss of near vision associated with presbyopia; TAB014, a clinical-stage bevacizumab-based antibody indicated for wAMD; and PAN-90806 a drug indicated in the treatment of wAMD and DME. In addition, the company develops ZK002, a protein with a novel mechanism of action to contain inflammation and vascular flood leakage; Bimatoprost, a generic drug used in the treatment of glaucoma; Levobetaxolol HCl, a generic eye drop used in the treatment of glaucoma to lower pressure in the eye; and Travoprost, a prescribed PGAs for open-angle glaucoma. Further, it is involved in the development of Bimatoprost Timolol for targeting glaucoma; Latanoprost Timolol, a PGA and ß blocker combination eye drop targeting glaucoma; Travoprost Timolol, a potential first-to-market generic travoprost timolol; and Latanoprost, a prescribed PGAs for open-angle glaucoma. The company was formerly known as China Ophthalmology Focus Limited. Zhaoke Ophthalmology Limited was incorporated in 2017 and is headquartered in Guangzhou, the People's Republic of China.

Price · split & dividend adjusted
News & notes moving 6622.HK
Biotech & Genomic Medicine▼

Qilu Pharmaceutical's atropine sulfate eye drops application accepted, intensifying competition in children's myopia drug market

Qilu Pharmaceutical's marketing application for atropine sulfate eye drops, filed under chemical drug registration category 2.2, was accepted by the Center for Drug Evaluation of the National Medical Products Administration on July 24. The indication is to slow the progression of myopia in children. Currently, only Xingqi Pharmaceutical's 0.01% atropine sulfate eye drops have been approved for marketing in this field, in March 2024, with nationwide sales reaching 603.6 million yuan in 2025, a year-on-year increase of 212%. Similar products from companies such as Hengrui Medicine's subsidiary Shengdi Pharmaceutical and Zhaoke Ophthalmology have also entered the marketing application stage, while Ocumension Therapeutics, Shapuaisi, and JMD Biomed are in late-stage clinical trials. Qilu Pharmaceutical stated that it is currently only an application, and the specific launch time is uncertain.
300573.CS ▲6622.HK ▼1477.HK ▼600276.CG ▼603168.CG ▼
Biotech & Genomic Medicine
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6622.HK▲

Zhaoke Ophthalmology Acquires Global Rights to Atropine Sulfate Eye Drops

Zhaoke Ophthalmology announced it has acquired the global rights to NVK002 atropine sulfate eye drops, a product designed to slow the progression of myopia in children. Under the agreement, Zhaoke Ophthalmology will obtain global ownership of all intellectual property, trademarks, regulatory filings, clinical data, manufacturing capabilities, and other assets related to NVK002. Previously, the company only held exclusive licenses for Greater China, South Korea, and some Southeast Asian countries. As part of the transaction, Zhaoke Ophthalmology granted the seller a perpetual, royalty-free exclusive license for development and commercialization in the United States. After the acquisition, the company will have full control over the global development, manufacturing, and commercialization of the product. Currently, only Xingqi Ophthalmology has received approval for atropine sulfate eye drops in China. Zhaoke Ophthalmology has submitted marketing applications for two strengths of NVK002 as a modified new drug and a generic drug respectively, with approval expected within the year. Several other pharmaceutical companies, including Hengrui Medicine and Ocumension Therapeutics, are also developing similar products.
6622.HK ▲1477.HK ▼600276.CG ▼300573.CS ▲
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