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Contineum Therapeutics, Inc. Class A Common Stock

Contineum Therapeutics, Inc. is a clinical-stage biopharmaceutical company that develops small-molecule therapies for neuroscience, inflammation, and immunology indications in the United States. Its lead asset, PIPE-791, is a novel, brain-penetrant small-molecule inhibitor of the lysophosphatidic acid 1 receptor (LPA1R) being developed for idiopathic pulmonary fibrosis and chronic pain. The company also develops PIPE-307, a novel small-molecule inhibitor of the muscarinic type 1 receptor for depression and relapse-remitting multiple sclerosis. Formerly known as Pipeline Therapeutics, Inc., it changed its name to Contineum Therapeutics, Inc. in November 2023. Incorporated in 2009, the company is based in San Diego, California.

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Contineum Therapeutics Reports Second-Quarter 2026 Financial Results and Affirms Key Clinical Milestones

Contineum Therapeutics reported its second-quarter 2026 financial results and affirmed key clinical development milestones. The company's cash, cash equivalents and marketable securities totaled $236.6 million as of June 30, 2026, which it believes is sufficient to fund operations through mid-2029. Research and development expenses decreased 10 percent to $12.7 million, while general and administrative expenses rose 23 percent to $4.7 million, resulting in a net loss of $15.2 million for the quarter. On the clinical front, Contineum's global Phase 2 PROPEL-IPF trial evaluating PIPE-791 for idiopathic pulmonary fibrosis has more than 55 sites online across eight countries, and Johnson & Johnson completed enrollment of 107 participants in its Phase 2 MOONLIGHT-1 trial of JNJ-5120/PIPE-307 for major depressive disorder. The company also streamlined its discovery programs, leading to a limited workforce reduction including the departure of its Chief Scientific Officer.
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