Tenaya Therapeutics, Inc. is a clinical-stage biotechnology company focused on discovering, developing, and delivering therapies for heart disease in the United States. Its lead product candidates include TN-201, a gene therapy for myosin binding protein C3-associated hypertrophic cardiomyopathy in Phase 1b/2 clinical trials; TN-401, a gene therapy for plakophilin 2-associated arrhythmogenic right ventricular cardiomyopathy in Phase 1b/2 clinical trials; and TN-301, a small molecule histone deacetylase-6 for heart failure with preserved ejection fraction in Phase 1 clinical trials. The company develops its products through gene addition, gene editing, gene silencing, and cellular regeneration. It has a research collaboration agreement with Alnylam Pharmaceuticals, Inc. to identify and validate novel gene targets for the potential treatment of cardiovascular disease. Tenaya Therapeutics, Inc. was incorporated in 2016 and is headquartered in South San Francisco, California.