Hualan Biological Engineering Inc. and its subsidiaries research, develop, produce, and sell biological products in China and internationally. The company offers blood products such as human serum albumin, human prothrombin complex concentrate, human coagulation factor VIII, human fibrinogen, and freeze-dried human fibrin glue for surgical use, as well as intravenous, human, rabies, hepatitis B, and tetanus immunoglobulin. It also provides vaccines, including influenza virus split, H1N1 influenza A virus split, quadrivalent influenza virus split, group A and C meningococcal polysaccharide, group ACYW135 meningococcal polysaccharide, recombinant hepatitis B vaccine, freeze-dried human rabies, and adsorbed tetanus vaccines. In addition, the company develops monoclonal antibody drugs and biosimilars: rituximab injection (Phase III for CD20-positive diffuse large B-cell/follicular non-Hodgkin lymphoma and chronic lymphocytic leukemia), adalimumab injection (Phase III for autoimmune diseases), denosumab injection (Phase III for bone metastases), injectable trastuzumab (Phase III for HER2-positive metastatic/early-stage breast cancer and metastatic gastric cancer), and recombinant Exendin-4-FC fusion protein injection (Phase I/II for type 2 diabetes). It is also involved in poultry farming research and development, plasma collection, engineering technology research and experimental development, and inspection and testing services. Founded in 1992, the company is headquartered in Xinxiang, China.