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Verrica Pharmaceuticals Doses First U.S. Patient in Second Pivotal Common Warts Trial
Verrica Pharmaceuticals announced that the first U.S. patient has been dosed in COVE-3, the second pivotal clinical trial of its global Phase 3 program evaluating YCANTH for the treatment of common warts. The company's Japanese development partner, Torii Pharmaceutical, also recently dosed the first Japanese patient in the same study. The Phase 3 program consists of two double-blind, randomized, vehicle-controlled trials, with COVE-2 enrolling only in the U.S. and COVE-3 enrolling in both the U.S. and Japan. Verrica noted that COVE-2 has already surpassed 50% of its targeted U.S. enrollment, and a long-term follow-up study, COVE-4, is also underway. If approved, YCANTH would be the first FDA-approved therapy for common warts, a condition affecting an estimated 22 million people in the U.S. alone.