4basebio PLC, together with its subsidiaries, researches, develops, manufactures, and sells synthetic DNA and RNA products in Europe, the United States, and internationally. Its offerings include hpDNA, a double-stranded linear DNA for viral and non-viral vector applications; opDNA, a partially opened linear double-stranded DNA for in vitro transcription processes that produce mRNA for vaccines and therapeutics; oeDNA, a linear double-stranded DNA for genome editing; osDNA, a DNA product with nucleotide modifications within the DNA backbone; and Hermes, a nanoparticle platform. The company also provides custom pegRNA and sgRNA manufacturing and nanoparticle formulation services. Its products are used in mRNA vaccines and therapies, viral vectors, gene editing, DNA vaccines, and non-viral delivery applications. Formerly known as 4basebio UK Societas, it changed its name to 4basebio PLC in July 2021, was founded in 2008, and is headquartered in Cambridge, the United Kingdom.