Akebia Therapeutics, Inc. is a biopharmaceutical company focused on developing and commercializing therapeutics for patients with kidney diseases. Its product portfolio includes Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase inhibitor for anemia due to chronic kidney disease (CKD) in dialysis-dependent (DD) and non-dialysis dependent (NDD) patients, and Auryxia, a ferric citrate used to control serum phosphorus levels in adult patients with DD-CKD and to treat iron deficiency anemia in adult patients with NDD-CKD. The company is also developing AKB-9090 in Phase 2 clinical trials for cardiac surgery-related acute kidney injury and acute respiratory distress syndrome, and AKB-10108 for retinopathy of prematurity in neonates. Akebia has license and collaboration agreements with Tanabe Pharma Corporation for Vafseo in Japan and other Asian countries, as well as agreements with CSL Vifor, Averoa, Panion & BF Biotech, Cyclerion Therapeutics, and Q32. Incorporated in 2007, the company is headquartered in Cambridge, Massachusetts.