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Dogwood Therapeutics, Inc.

Dogwood Therapeutics, Inc. is a development-stage biotechnology company focused on developing medicines for pain and fatigue-related disorders. Its lead candidates include IMC-1, a famciclovir and celecoxib combination that completed a Phase 2b trial for fibromyalgia; Halneuron, in Phase 2b for chemotherapy-induced neuropathic pain and cancer pain, and in preclinical development for acute surgical pain; IMC-2, a valacyclovir and celecoxib combination intended to suppress herpesvirus activation; and Serpin Peptide 16, in early Phase 1 for reducing neuropathy caused by neurotoxic chemotherapeutic agents. Formerly Virios Therapeutics, Inc., it changed its name to Dogwood Therapeutics, Inc. in October 2024. Founded in 2012, it is based in Alpharetta, Georgia.

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Biotech & Genomic Medicine

Dogwood Enrolls First 200 Patients in Halneuron Phase 2b Chemotherapy Neuropathy Trial

Dogwood Therapeutics has enrolled the first 200 patients in its ongoing HAL-CINP Phase 2b trial of Halneuron for chemotherapy-induced neuropathic pain, with top-line data expected in fall 2026. The trial is designed to enroll approximately 210 to 240 patients across about 25 U.S. sites, and an independent statistical review committee has already observed separation from placebo in pain improvement. The dropout rate stands at 4.5%, which the company says is below rates typically seen in studies of other FDA-approved chronic pain medicines. Halneuron is a non-opioid NaV 1.7 analgesic that has received fast track designation from the FDA for this indication.
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