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Lantern Pharma Inc

Lantern Pharma Inc. is a biotechnology company focused on the discovery and development of oncology drugs in India. Its pipeline includes LP-300, in phase 2 trials as a combination therapy for never-smokers with non-small cell lung cancer adenocarcinoma; LP-184, in phase 1a trials for advanced or metastatic solid tumors, unresectable or recurrent GBM, and other solid tumors such as pancreatic, breast, bladder, and lung cancers, as well as glioblastoma and other central nervous system cancers; and LP-284, in phase 1 trials for non-Hodgkin's lymphomas, including mantle cell lymphoma and double hit lymphoma. The company also develops STAR-001, in preclinical development for glioblastoma, brain metastases, atypical teratoid rhabdoid tumors, and several rare pediatric CNS cancers, and provides an ADC program, an antibody drug conjugate therapeutic approach for cancer treatment. It has a strategic AI-driven collaboration with Oregon Therapeutics to optimize the development of its first-in-class protein disulfide isomerase inhibitor drug candidate XCE853 in novel and targeted cancer indications; a collaboration agreement with TTC Oncology focused on the drug development of TTC-352 to treat patients with metastatic ER+ breast cancer; and a collaboration agreement with Actuate Therapeutics, Inc. focused on the development of compounds for use in the treatment of cancer and inflammatory diseases leading to fibrosis. The company was incorporated in 2013 and is headquartered in Dallas, Texas.

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Biotech & Genomic Medicine

Lantern Pharma spins out Open Medicine AI, reports Q2 net loss

Lantern Pharma has established Open Medicine AI as a separate company with commercial licenses and agreements in place, a move CEO Panna Sharma called the most consequential structural decision since starting Lantern. The company reported a net loss of approximately $7.1 million, or $0.57 per share, for the second quarter of 2026, with R&D expenses of about $1.8 million and G&A expenses of about $1.7 million. Management highlighted a subgroup signal for LP-300 in never-smokers with non-small cell lung cancer after TKI therapy, where L858R patients who completed six cycles had a median progression-free survival of 8.9 months and a hazard ratio of 0.37. For LP-184, the company received clearance in July for an investigator-initiated Phase Ib/II trial in advanced bladder cancer, and an FDA-cleared protocol is moving toward launch for a monotherapy trial in relapsed/refractory triple-negative breast cancer. Cash, cash equivalents, and marketable securities were approximately $7.4 million at June 30, 2026, and management said additional funding is a top priority to extend the operating runway.
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