Surrozen, Inc. is a biotechnology company that discovers and develops product candidates to selectively modulate the Wnt pathway for tissue repair. Its lead candidates are antibody-based therapeutics targeting diseases of the eye, intestine, liver, lung, retina, kidney, cochlea, cornea, skin, pancreas, and central nervous system. The company is developing SZN-814, which combines Frizzled 4 (Fzd4) agonism and vascular endothelial growth factor (VEGF) antagonism for diabetic macular edema (DME), neovascular age-related macular degeneration (wet AMD), and retinopathy; SZN-8143, which combines Fzd4 agonism, VEGF antagonism, and interleukin-6 (IL-6) for DME, wet AMD, and uveitic macular edema; and SZN-413, a Fzd4-targeted bi-specific antibody for retinal vascular associated diseases. Surrozen has a collaboration and license agreement with Boehringer Ingelheim International GmbH to research, develop, and commercialize Fzd4 bi-specific antibodies, and a research collaboration agreement with TCGFB, Inc. to discover antibody therapeutics targeting transforming growth factor beta (TGF-ß) for idiopathic pulmonary fibrosis. Founded in 2015, Surrozen is headquartered in South San Francisco, California.