Zhejiang Hisun Pharmaceutical Co LtdHisun secures exclusive license for TISA-818, a novel drug with promising Phase I/IIa results, expanding its pipeline.

Hisun Pharmaceutical has signed an exclusive product license and collaboration agreement with Aitia Shanghai Pharmaceuticals. The deal grants Hisun the rights to develop, register, manufacture, and commercialize the Class 1 innovative chemical drug TISA-818 systemic formulation in mainland China, Hong Kong, and Macau, making it the marketing authorization holder in the region. The company will pay an upfront fee of 45 million yuan, with cumulative development milestone payments capped at 100 million yuan, and sales milestone rewards based on a percentage of annual net sales, up to a maximum of 200 million yuan. TISA-818 is a novel mechanism drug that modulates immune responses through multiple targets and pathways, offering anti-inflammatory effects without immunosuppression. It has completed a Phase I clinical trial for pulmonary fibrosis in Europe and a Phase IIa trial for acute respiratory distress syndrome in China, demonstrating promising therapeutic potential.
Zhejiang Hisun Pharmaceutical Co LtdHisun secures exclusive license for TISA-818, a novel drug with promising Phase I/IIa results, expanding its pipeline.