Ulcerative Colitis Market to Reach $9.4B by 2036, Late-Stage Drugs Advance

Industry
โดย GlobeNewswire·US·Read original
Summary · why it matters

DelveInsight projects the ulcerative colitis market across the seven major markets—the US, EU4, UK, and Japan—will grow from approximately USD 9.4 billion in 2025 at a CAGR of 7.6% through 2036, driven by novel targeted therapies and a robust pipeline of late-stage candidates. Among these, Abivax's obefazimod, a first-in-class oral miR-124 enhancer, met its primary endpoint in Phase III ABTECT induction studies, with a pooled placebo-adjusted clinical remission rate of 16.4% at Week 8. Merck's tulisokibart, acquired via Prometheus Biosciences, achieved clinical remission in the Phase 3 ATLAS-UC study, while Roche's afimkibart, from its $7.1 billion Telavant acquisition, showed a 35% remission rate in Phase IIb TUSCANY-2. Johnson & Johnson and Protagonist Therapeutics' icotrokinra, a first-in-class oral IL-23 receptor antagonist, met its primary endpoint in the Phase 2b ANTHEM-UC trial, and Teva and Sanofi's duvakitug, backed by a $400 million Blackstone funding deal, is in Phase III. These therapies target unmet needs in moderate-to-severe disease, with the market shifting toward IL-23 inhibitors and oral advanced therapies, though biosimilars and established anti-TNFs remain widely used.

Impact on stocks 10

Biotech & Genomic Medicine▲ · 5 stocks
Abivax SA
ABVX
▲ PositiveTechnologyrelevance

Abivax's obefazimod met its primary endpoint in Phase III ABTECT induction studies with a 16.4% placebo-adjusted remission rate.

Johnson & Johnson
JNJ
▲ PositiveTechnologyrelevance

J&J and Protagonist's icotrokinra met its primary endpoint in the Phase 2b ANTHEM-UC trial for ulcerative colitis.

Merck & Company Inc
MRK
▲ PositiveTechnologyrelevance

Merck's tulisokibart, acquired via Prometheus Biosciences, achieved clinical remission in the Phase 3 ATLAS-UC study.

Protagonist Therapeutics Inc
PTGX
▲ PositiveTechnologyrelevance

Protagonist Therapeutics' icotrokinra, partnered with J&J, met its primary endpoint in the Phase 2b ANTHEM-UC trial.

Health Care▲ · 3 stocks
Roche Holding AG
ROP
▲ PositiveTechnologyrelevance

Roche's afimkibart (from the $7.1B Telavant acquisition) showed a 35% remission rate in Phase IIb TUSCANY-2 for ulcerative colitis.

Sanofi SA
SAN
▲ PositiveTechnologyrelevance

Sanofi and Teva's duvakitug is in Phase III for ulcerative colitis, backed by a $400 million Blackstone funding deal.

Artificial Intelligence▲ · 1 stocks
Critical Materials & Supply Chain▲ · 1 stocks

Theme Impact 1

Off-coverage companies 1

Prometheus BiosciencesPrivate± Mixed
relevance

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