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Scynexis Inc

SCYNEXIS, Inc. is a biotechnology company focused on developing drugs for the treatment and prevention of difficult-to-treat and drug-resistant fungal infections in the United States. The company offers BREXAFEMME for patients with vulvovaginal candidiasis and for reducing the incidence of recurrence. It also develops SCY-247, which is in Phase I clinical trials for invasive fungal infections. Formerly known as SCYNEXIS Chemistry & Automation, Inc., it changed its name to SCYNEXIS, Inc. in June 2002, was incorporated in 1999, and is headquartered in Jersey City, New Jersey.

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Biotech & Genomic Medicine

SCYNEXIS swings to second-quarter profit, guides Phase 1 SCY-770 data in Q3 2026

SCYNEXIS reported a second-quarter net profit of $7.40 million, or $0.63 per share, swinging from a net loss of $6.89 million, or $1.11 per share, a year earlier. License agreement revenue fell to $0.24 million from $1.36 million. The company said its Phase 1 study of SCY-770, an investigational AMPK activator for Autosomal Dominant Polycystic Kidney Disease, will deliver topline data in the third quarter of 2026, with a Phase 2 proof-of-concept trial set to begin in the fourth quarter and an early efficacy readout expected in the second half of 2027. SCYNEXIS also completed dosing in the Phase 1 study of the IV formulation of SCY-247 and expects topline data in the third quarter. Cash, cash equivalents and investments totaled $71.1 million as of June 30, providing a runway into 2029. Shares rose 2.81% to $5.30 in after-hours trading.
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SCYNEXIS reports Q2 GAAP EPS of $0.63, beating estimates by $1.14

SCYNEXIS reported second-quarter 2026 financial results, posting GAAP earnings per share of $0.63, which exceeded analyst expectations by $1.14. Revenue came in at $0.24 million, an 82.4% decline year-over-year, yet still beat estimates by $0.16 million. The company's cash, cash equivalents and investments totaled $71.1 million as of June 30, 2026, up from $56.3 million at the end of 2025.
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