HighTide Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for chronic metabolic and liver diseases in Mainland China. Its lead candidate, HTD1801, is in Phase III trials for type 2 diabetes mellitus, Phase I for gradual loss of kidney function, Phase IIb for pathogenetic complexity and heterogeneity, Phase I for obesity, and Phase II for chronic cholestatic liver disease. The company is also developing HTD4010 (Phase I for alcoholic hepatitis), HTF1037 (preclinical for obesity and comorbidities), HTF1057 (preclinical for neurodegenerative diseases), HTD1804 (preclinical for obesity), and HTD1805 (preclinical for metabolic diseases). Founded in 2011, HighTide Therapeutics is headquartered in Shenzhen, China.